Haemolysis Effect Estimation of Doxycycline Hyclate 150 mg Delay Release Tablet in Bio-analysis (Human Plasma) by Liquid Chromatography-Tandem Mass Spectrometry
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چکیده
منابع مشابه
Determination of Mebudipine in Human Plasma by Liquid Chromatography–tandem Mass Spectrometry
In previous studies, mebudipine, a dihydropyridine calcium channel blocker, showed a considerable potential to be used in cardiovascular diseases. The aim of the current study was to develop a valid method using reversed-phase high performance liquid chromatography coupled with electrospray ionization mass spectrometry to assay mebudipine in the human plasma. Separation was achieved on a Zorbax...
متن کاملDetermination of Mebudipine in Human Plasma by Liquid Chromatography–tandem Mass Spectrometry
In previous studies, mebudipine, a dihydropyridine calcium channel blocker, showed a considerable potential to be used in cardiovascular diseases. The aim of the current study was to develop a valid method using reversed-phase high performance liquid chromatography coupled with electrospray ionization mass spectrometry to assay mebudipine in the human plasma. Separation was achieved on a Zorbax...
متن کاملdetermination of mebudipine in human plasma by liquid chromatography–tandem mass spectrometry
in previous studies, mebudipine, a dihydropyridine calcium channel blocker, showed a considerable potential to be used in cardiovascular diseases. the aim of the current study was to develop a valid method using reversed-phase high performance liquid chromatography coupled with electrospray ionization mass spectrometry to assay mebudipine in the human plasma. separation was achieved on a zorbax...
متن کاملLiquid chromatography–tandem mass spectrometry (LC-MS) method for the assignment of enalapril and enalaprilat in human plasma
A rapid and sensitive liquid chromatography–tandem mass spectrometry (LC-MS) method was developed for the determination of enalapril and enalaprilat in human plasma. Detection of analytes was achieved by tandem mass spectrometry with electrospray ionization (ESI) interface in positive ion mode which was operated under the multiple-reaction monitoring mode. Sample pretreatment was involved...
متن کاملKeywords: Liquid Chromatography Tandem Mass Spectrometry, Simvastatin, Human plasma
IntrOductIOn Simvastatin is cholesterol-lowering drug which competitively inhibits the cholesterol biosynthesis by HMG-CoA reductase [1]. Simvastatin is chemically modified 2,2-dimethyll butyrate analogue of lovastatin [2]. Simvastatin is orally administered as inactive prodrug in the lactone form which is converted in the liver into its active metabolite β-hydroxy acid [3]. Recently, numerous ...
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ژورنال
عنوان ژورنال: Journal of Bioequivalence & Bioavailability
سال: 2013
ISSN: 0975-0851
DOI: 10.4172/jbb.1000161